Lab Modules

In 2019, CBI partnered with UMass BTP (Biotech Training Program) to create Laboratory Modules designed to take advantage of the many new state-of-the-art facilities and instruments in the UMass Institute for Applied Life Sciences (IALS Core Facilities). These 2-3 day modules provide hands-on training and experience for graduate students, post-docs, and professors across chemistry, biology, chemical engineering, microbiology, and biochemistry departments. CBI trainees complete 4 laboratory modules of their choice as part of their training, providing the opportunity to explore new techniques, enhance their current research, and gain training for their post-PhD careers. IALS-focused modules are listed below; for all offerings, see BTP listing of all Lab modules.

Fall 2019:

Live-cell quantitative fluorescence microscopy

This lab module will introduce fundamental concepts of fluorescence microscopy using living tissue culture cells. After learning about the principles, strengths, and weaknesses of different approaches, participants will apply and compare wide-field fluorescence imaging, spinning disk and point scanning confocal imaging, and structured illumination microscopy (SIM) super-resolution imaging – all on living samples. Participants will learn how to control multiple microscopy systems (hardware) using the NIS-Elements software platform. The training will also include quantitative image analysis of data acquired in the module.

Instructor(s): Tom Maresca, Biology Associate Professor and James Chambers, Director of Light Microscopy Core Facility
Dates/times: December 12th (9AM-4PM) and 13th: (9AM-4:30PM)
Location: Nikon Center of Excellence, S576A Life Science Laboratories
Max number of participants: 6-10
Sign up: email cbiassist@umass.edu until max capacity

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Molecular Modeling and Simulation Using Computational Approaches

Molecular modeling and simulation provide crucial insights into the structure, dynamics, and interactions of various systems at the molecular level, to both complement and enrich experimental measurements. This lab module training will introduce basic theories of popular modeling and simulation approaches, including molecular visualization, molecular dynamics simulation, quantum chemistry calculation, and molecular docking. The training also provides hands-on tutorials of widely-used software packages.

Instructor: Chungwen Liang (Director, IALS Computational Modeling Core)
Dates/Times: 8/2, 8/5  (9:00 am ~ 5:00 pm)
Location: Biology Computer Resource Center, 311 Morrill Science Center, Building III South
Max number of participants:  20
Sign up: email cbiassist@umass.edu until max capacity