Chalk Talk

The monthly CBI Chalk Talk is a highlight of the program and brings the community together to learn about cutting edge research. In each half of a Chalk Talk, the faculty advisor introduces the problems being tackled using only “chalk” on the chalk board – this forces a big picture overview, accessible to all. A student from the lab then presents recent research results, again with a focus on broad accessibility. Discussion is highly encouraged and is generally vibrant! After the two Chalk Talks, everyone convenes for a pizza lunch, just outside of the seminar room, for still more discussion of the talks!

Upcoming Chalk Talks

Chalk Talk Poster 2020-2021 Chalk Talk 2020-2021 Schedule

Date: See poster for Fall 2020 and Spring 2021 dates
Location: Fall 2020 – Virtual; Spring 2021 – TBA

Chalk Talk Feb 3, 2020 – Lynmarie Thompson and Richard Vachet

Title of the talk” – TBA
Student Speaker (Thompson Lab)

Title of the talk” – TBA
Student Speaker (Vachet Lab)

Please see our full dates for Fall 2020-Spring 2021 and presenting labs here.

Past Chalk Talks

Chalk Talk Dec 2, 2020 – S. Thai Thayumanavan and Patrick Flaherty Labs

Estimating Subclonal Populations from Structured DNA Sequencing Data
Student Speaker – Shai He (Flaherty Lab)

Antibody – Nanoparticle Conjugates for Targeted Delivery of Chemotherapeutics
Student Speaker – Khushboo Singh (Thayumanavan Lab)

Chalk Talk Nov 4, 2020 – Eric Strieter and Mingxu You Labs

A Cryptic Site on the  Proteasome-Associated Deubiquitinase UCH37/UCHL5 is Required for Chain Editing and Degradation
Student Speaker – Jiale Du (Strieter Lab)

“Real-time Monitoring of Transient Lipid-Lipid Interactions in Live Cell Membranes using a DNA Prob
Student Speaker – Yousef Bagheri Zarringhabae (You Lab)

Multiplex Imaging in Living Cells with Fluorogenic RNAs
Student Speaker – Ru Zheng (You Lab)

Chalk Talk Oct 7, 2020 – Jeanne Hardy and Amanda Woerman Labs

Studying allosteric sites on caspase-6 to aid the development of substrate-specific inhibitors
Student Speaker: Irina Sagarbarria and Andrew J. Smith (Hardy Lab)

Investigating alpha-synuclein aggregation using novel models of strain competition
Student Speaker: Sarah Holec (Woerman Lab)

Chalk Talk Sept 9, 2020 – Jennifer Rauch and Jianhan Chen Labs

Physical Origins of DnaK-substrate binding revealed through Physics-based modeling
Erik Nordquist (J. Chen Lab)

Targeting Tau “The spread and aggregation of the protein tau has been linked to a variety of neurodegenerative diseases, known as tauopathies. Mounting evidence suggests that the spread of tau aggregates may underlie disease phenotype, however the mechanism for this toxicity is still unknown. The Rauch lab uses a variety of cell biology, biochemical, and in vivo techniques to characterize consequences of tau propagation in the central nervous system and to define/target the molecular requirements for tau spread. As the newest faculty to the BMB department, Jenny will give a brief overview of exciting projects that will be starting in her lab this upcoming January.”
Rauch Lab, new incoming BMB Assistant Professor beginning in January 2021.

Chalk Talk Apr 15, 2020 – CBI Trainees!

Great talks and discussions with 78 attending this first-ever Zoom Chalk Talk!

Andrew Smith (Hardy lab) “Studying protein interactions to identify caspase exosites”

Nathan Canniff (Hebert lab) “Characterization of Putative ER Adaptors/Co-Chaperones TTC13 and TTC17”

Heather Bisbee (Strieter lab) “The Proteasomal Deubiquitinase UCH37 Promotes Degradation In Cellulo”

Katie Wahlbeck (Thompson lab) “Investigation of CheA Protein Dynamics with Solid State NMR”

Chalk Talk Mar 11, 2020 – Jessica Schiffman and Sarah Perry Labs

Sarthak Saha (Perry Lab) “Protein Crystallography using X-ray compatible Microfluidic Devices”

Mengfei Huang (Schiffman Lab)“High-Performance Coatings Featuring Methylene Malonate Derivatives”

Chalk Talk Feb 12, 2020 – Alejandro Heuck and Michelle Farkas Labs

Sujeewa S. Lellupitiyage Don (Farkas Lab) “Tracking and Modulating Circadian Rhythms in Cell Culture Models of Breast Cancer”

Hanling Guo (Heuk Lab) “Searching for inhibitors of Type III secretion translocon assembly”

Chalk Talk Jan 22, 2020 – Joe Jerry and Tricia Serio Labs

Teal Brechtel (Serio Lab) “Chaperone Titration as a Mechanism of Amyloid Appearance”

Aman Sharma (Jerry Lab) Estrogen-mediated R-loop formation associated with DNA damage may indicate individual vulnerability to breast cancer”

Chalk Talk Dec 11, 2019 – Meg Stratton and Craig Martin Labs

Can Özden (Stratton Lab) “CaMKII role in Long-Term Memory”

Elvan Cavaç and Kithmie MalagodaPathiranage (Martin Lab) “RNA for Next Generation Everything”

Chalk Talk Nov 6, 2019 – Peyton and Chien Labs

Carey Dougan (Peyton lab) “The Role of Cavitation in Traumatic Brain Injury (TBI)”

Christine Battle and Tommy Tashjian (Chien lab) “How to Get Away with Murder – Protein Destruction by Energy Dependent Proteases”