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Chalk Talk

Chalk Talk Apr 15, 2020 – CBI Trainees!

Great talks and discussions with 78 attending this first-ever Zoom Chalk Talk!

Andrew Smith (Hardy lab) “Studying protein interactions to identify caspase exosites”

Nathan Canniff (Hebert lab) “Characterization of Putative ER Adaptors/Co-Chaperones TTC13 and TTC17”

Heather Bisbee (Strieter lab) “The Proteasomal Deubiquitinase UCH37 Promotes Degradation In Cellulo”

Katie Wahlbeck (Thompson lab) “Investigation of CheA Protein Dynamics with Solid State NMR”

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Chalk Talk

Chalk Talk Mar 11, 2020 – Jessica Schiffman and Sarah Perry Labs

Sarthak Saha (Perry Lab) “Protein Crystallography using X-ray compatible Microfluidic Devices”

Mengfei Huang (Schiffman Lab)“High-Performance Coatings Featuring Methylene Malonate Derivatives”

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Chalk Talk

Chalk Talk Feb 12, 2020 – Alejandro Heuck and Michelle Farkas Labs

Sujeewa S. Lellupitiyage Don (Farkas Lab) “Tracking and Modulating Circadian Rhythms in Cell Culture Models of Breast Cancer”

Hanling Guo (Heuk Lab) “Searching for inhibitors of Type III secretion translocon assembly”

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Chalk Talk

Chalk Talk Jan 22, 2020 – Joe Jerry and Tricia Serio Labs

Teal Brechtel (Serio Lab) “Chaperone Titration as a Mechanism of Amyloid Appearance”

Aman Sharma (Jerry Lab) Estrogen-mediated R-loop formation associated with DNA damage may indicate individual vulnerability to breast cancer”

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CBI Faculty

Lynmarie Thompson

Mechanisms of Membrane Receptors in Signaling – NMR and Mass Spec Studies

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CBI Faculty

Eric Strieter

Protein post-translational modifications

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CBI Faculty

Craig Martin

New mechanism-based approaches for improved in vitro RNA synthesis

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Chalk Talk

Chalk Talk Dec 11, 2019 – Meg Stratton and Craig Martin Labs

Can Özden (Stratton Lab) “CaMKII role in Long-Term Memory”

Elvan Cavaç and Kithmie MalagodaPathiranage (Martin Lab) “RNA for Next Generation Everything”

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Testimonials

I just love CBI

you betcha

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Chalk Talk

Chalk Talk Nov 6, 2019 – Peyton and Chien Labs

Carey Dougan (Peyton lab) “The Role of Cavitation in Traumatic Brain Injury (TBI)”

Christine Battle and Tommy Tashjian (Chien lab) “How to Get Away with Murder – Protein Destruction by Energy Dependent Proteases”

Misfolding of WordPress Nanoparticles

Craig Martin. University of Massachusetts Amherst

Nov 15, 2019. LGRT 371

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Chalk Talk

Oct 9, 2019 – Elizabeth Vierling and Maria Santore Labs

Minsoo Kim (Vierling Lab) “Breathing and Communication are Key to Life”

Weiyue Xin (Santore Lab) “Biological Membranes in the Materials World: How Curvature and Tension Influence the Assembly of Biomolecules”

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Chalk Talk

Sept 11, 2019 – Scott Garman Lab

Efecan Aral (Garman Lab) “Identifying effects of Fabry disease mutations to enable personalized medicine”

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Ice Cream Social

CBI in July 2019 – Ice Cream Social

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News & Events

Lila Gierasch elected to the National Academy of Sciences!

Read the press release and her member profile!

Lila’s research focus for decades has been protein folding, that is, how amino acid sequence determines the three-dimensional structure of a protein. She is particularly focused on how proteins fold in the cellular environment and the role of molecular chaperones in ensuring high fidelity in the folding process.

Lila says of her selection, “I am thrilled by this honor. The recognition of one’s contributions over a career by colleagues is truly gratifying.”

The National Academy of Sciences (NAS) is a private, non-profit society of distinguished scholars established by an Act of Congress signed by President Abraham Lincoln in 1863. The academy is charged with providing independent, objective advice to the nation on matters related to science and technology. Scientists are elected by their peers to membership in the NAS for outstanding contributions to research.

NAS is committed to furthering science in America, and its members are active contributors to the international scientific community. Nearly 500 members of the NAS have won Nobel Prizes. This year’s group, which also includes 25 non-voting associate members, citizens of foreign countries, brings the total number of active members to 2,347 and the total number of foreign associates to 487. The society’s journal, Proceedings of the National Academy of Sciences, founded in 1914, is one of the premier international journals publishing results of original research.

In 2018, Lila received the American Chemical Society’s Ralph F. Hirschmann Award in Peptide Chemistry for “her seminal contributions to peptide structure and function, peptide models for protein folding and function, and roles of peptide and protein aggregation in disease.” In 2016, she was elected to the American Academy of Arts and Sciences. That same year, the American Society for Biochemistry and Molecular Biology named her editor in chief of the Journal of Biological Chemistry, the society’s flagship journal, for a five-year term. In 2014, she was named to the National Institutes of Health Council of Councils, established to advise the NIH director on policies and activities of the Division of Program Coordination, Planning and Strategic Initiatives, which includes making recommendations on research that represents important areas of emerging scientific opportunities, rising public health challenges or knowledge gaps that deserve special emphasis or would otherwise benefit from strategic planning and coordination.

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Chalk Talk

Apr 24, 2019 – Mingxu You and Lila Gierasch Labs

Rigumula Wu (You Lab) “Fluorogenic RNA-based Sensors for Quantitative Imaging in Living Cells”

Bin Zhao (You Lab) “Push It, Pull It: Critical Roles of Mechanical forces in biological processes”

Wenli Meng (Gierasch Lab) “Hsp 70 as hub of cellular proteostasis network”

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Chalk Talk

Mar 20, 2019 – Eric Strieter and Dan Hebert Labs

Ben Adams (Hebert Lab) “The Interplay of quality control pathways of the endoplasmic reticulum.”

Jiale Du (Strieter Lab) “Interrogating the Selectivity of Proteasome Associated Deubiquitinase UCH37.”

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Chalk Talk

Feb 13, 2019 – CBI Trainees!

Sandor Babik (Streiter Lab) “Interrogating Branched Ubiquitin Chains by NMR Spectroscopy and Computational Methods”

Samar Mahmoud (Chien Lab) “Exploring Lon-related pathways using a Non-Essential Phenotypic Suppressor Screen”

Javier Mas (Farkas Lab) “Understanding Macrophage Polarization and Re-Education in the Context of Cancer”

Weiyue Xin (Santore Lab) “The impact of curvature and solid mechanics on domain patterns in molecular thin materials”

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Chalk Talk

Jan 23, 2019 – Vince Rotello and Mike Knapp Labs

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Chalk Talk

Dec 12, 2018 – Jianhan Chen and Greg Tew Labs

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Chalk Talk

Nov 7, 2018 – Sloan Siegrist and Thai Thayumanavan Labs

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Chalk Talk

Oct 10, 2018 – Lynmarie Thompson and Richard Vachet Labs

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Chalk Talk

Sept 12, 2018 – Min Chen & Jeanne Hardy Labs