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Chalk Talk

Chalk Talk May 5, 2021 – CBI Trainees

Force-responsive Materials Utilizing Cryptic Crosslinking Sites
Adrian Lorenzana (Peyton Lab)

Establishing Adhesive Responses of Uropathogenic E. coli to Gels with Various Stiffnesses
Brandon Barajas (Schiffman Lab)

Metabolic Labeling as a Discovery Tool for Cell Wall Recycling
Rebecca Gordon (Siegrist Lab)

Chemical labeling of Mycobacteria for growth monitoring and detection
Kiserian Jackson (Siegrist Lab)

Please see our full dates for Fall 2020-Spring 2o21 and presenting labs here.

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Chalk Talk

Chalk Talk April 7, 2021 – Min Chen & Vince Rotello

Direct Cytosolic Delivery of GFP and the Awesome Power of Nuclear Fluorescence
David Luther (Rotello Lab)

Development of a Multiplex OmpG Biosensor
Josh Foster (M. Chen Lab)

Studying the conformational dynamics of Abl kinase in real time with a nanopore tweezer
Fanjun Li (M. Chen Lab)

Please see our full dates for Fall 2020-Spring 2o21 and presenting labs here.

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Chalk Talk

Chalk Talk March 3, 2021 – Yasu Morita and Dan Hebert

Polyprenol biosynthesis in the maintenance and regulation of mycobacterial membrane domain
Student Speaker -Malavika Prithviraj (Yasu Lab )

Understanding the selectivity of the UGGTs, key quality control sensors and gatekeepers of the mammalian secretory pathway
Student Speaker – Kevin Guay (Hebert Lab)

The identification and characterization of a putative ER adapter protein TTC17
Student Speaker – Nathan Canniff (Hebert Lab)

Please see our full dates for Fall 2020-Spring 2021 and presenting labs here.

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Chalk Talk

Chalk Talk Feb 3, 2021 – Lynmarie Thompson and Richard Vachet

“Investigating E. coli CheA Activation by Chemoreceptors using Hydrogen Deuterium Exchange Mass Spectrometry”
Student Speaker – Thomas Tran (Thompson Lab)

“DNA-Mediated Assembly of Functional Chemoreceptors: Using Structural DNA Nanotechnology to Advance Biophysical Research” Student Speaker – Tiernan Kenneday (Thompson Lab)

“Membrane Protein Structure and Binding Interactions Studied by Mass Spectrometry” Student Speaker – Xiao Pan (Vachet Lab)

Please see our full dates for Fall 2020-Spring 2021 and presenting labs here.

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Chalk Talk

Chalk Talk Dec 2, 2020 – S. Thai Thayumanavan and Patrick Flaherty Labs

Estimating Subclonal Populations from Structured DNA Sequencing Data
Student Speaker – Shai He (Flaherty Lab)

Antibody – Nanoparticle Conjugates for Targeted Delivery of Chemotherapeutics
Student Speaker – Khushboo Singh (Thayumanavan Lab)

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Chalk Talk

Chalk Talk Nov 4, 2020 – Eric Strieter and Mingxu You Labs

A Cryptic Site on the  Proteasome-Associated Deubiquitinase UCH37/UCHL5 is Required for Chain Editing and Degradation
Student Speaker – Jiale Du (Strieter Lab)

“Real-time Monitoring of Transient Lipid-Lipid Interactions in Live Cell Membranes using a DNA Prob
Student Speaker – Yousef Bagheri Zarringhabae (You Lab)

Multiplex Imaging in Living Cells with Fluorogenic RNAs
Student Speaker – Ru Zheng (You Lab)

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Chalk Talk

Chalk Talk Oct 7, 2020 – Jeanne Hardy and Amanda Woerman Labs

Studying allosteric sites on caspase-6 to aid the development of substrate-specific inhibitors
Student Speaker: Irina Sagarbarria and Andrew J. Smith (Hardy Lab)

Investigating alpha-synuclein aggregation using novel models of strain competition
Student Speaker: Sarah Holec (Woerman Lab)

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Chalk Talk

Chalk Talk 2020-2021 Schedule

Date: See poster for Fall 2020 and Spring 2021 dates
Location: Fall 2020 – Virtual; Spring 2021 – Virtual

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Chalk Talk

Chalk Talk Sept 9, 2020 – Jennifer Rauch and Jianhan Chen Labs

Physical Origins of DnaK-substrate binding revealed through Physics-based modeling
Erik Nordquist (J. Chen Lab)

Targeting Tau “The spread and aggregation of the protein tau has been linked to a variety of neurodegenerative diseases, known as tauopathies. Mounting evidence suggests that the spread of tau aggregates may underlie disease phenotype, however the mechanism for this toxicity is still unknown. The Rauch lab uses a variety of cell biology, biochemical, and in vivo techniques to characterize consequences of tau propagation in the central nervous system and to define/target the molecular requirements for tau spread. As the newest faculty to the BMB department, Jenny will give a brief overview of exciting projects that will be starting in her lab this upcoming January.”
Rauch Lab, new incoming BMB Assistant Professor beginning in January 2021.

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Chalk Talk

Chalk Talk Apr 15, 2020 – CBI Trainees!

Great talks and discussions with 78 attending this first-ever Zoom Chalk Talk!

Andrew Smith (Hardy lab) “Studying protein interactions to identify caspase exosites”

Nathan Canniff (Hebert lab) “Characterization of Putative ER Adaptors/Co-Chaperones TTC13 and TTC17”

Heather Bisbee (Strieter lab) “The Proteasomal Deubiquitinase UCH37 Promotes Degradation In Cellulo”

Katie Wahlbeck (Thompson lab) “Investigation of CheA Protein Dynamics with Solid State NMR”

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Chalk Talk

Chalk Talk Mar 11, 2020 – Jessica Schiffman and Sarah Perry Labs

Sarthak Saha (Perry Lab) “Protein Crystallography using X-ray compatible Microfluidic Devices”

Mengfei Huang (Schiffman Lab)“High-Performance Coatings Featuring Methylene Malonate Derivatives”

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Chalk Talk

Chalk Talk Feb 12, 2020 – Alejandro Heuck and Michelle Farkas Labs

Sujeewa S. Lellupitiyage Don (Farkas Lab) “Tracking and Modulating Circadian Rhythms in Cell Culture Models of Breast Cancer”

Hanling Guo (Heuk Lab) “Searching for inhibitors of Type III secretion translocon assembly”

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Chalk Talk

Chalk Talk Jan 22, 2020 – Joe Jerry and Tricia Serio Labs

Teal Brechtel (Serio Lab) “Chaperone Titration as a Mechanism of Amyloid Appearance”

Aman Sharma (Jerry Lab) Estrogen-mediated R-loop formation associated with DNA damage may indicate individual vulnerability to breast cancer”

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Chalk Talk

Chalk Talk Dec 11, 2019 – Meg Stratton and Craig Martin Labs

Can Özden (Stratton Lab) “CaMKII role in Long-Term Memory”

Elvan Cavaç and Kithmie MalagodaPathiranage (Martin Lab) “RNA for Next Generation Everything”

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Chalk Talk

Chalk Talk Nov 6, 2019 – Peyton and Chien Labs

Carey Dougan (Peyton lab) “The Role of Cavitation in Traumatic Brain Injury (TBI)”

Christine Battle and Tommy Tashjian (Chien lab) “How to Get Away with Murder – Protein Destruction by Energy Dependent Proteases”

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Chalk Talk

Oct 9, 2019 – Elizabeth Vierling and Maria Santore Labs

Minsoo Kim (Vierling Lab) “Breathing and Communication are Key to Life”

Weiyue Xin (Santore Lab) “Biological Membranes in the Materials World: How Curvature and Tension Influence the Assembly of Biomolecules”

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Chalk Talk

Sept 11, 2019 – Scott Garman Lab

Efecan Aral (Garman Lab) “Identifying effects of Fabry disease mutations to enable personalized medicine”

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Chalk Talk

Apr 24, 2019 – Mingxu You and Lila Gierasch Labs

Rigumula Wu (You Lab) “Fluorogenic RNA-based Sensors for Quantitative Imaging in Living Cells”

Bin Zhao (You Lab) “Push It, Pull It: Critical Roles of Mechanical forces in biological processes”

Wenli Meng (Gierasch Lab) “Hsp 70 as hub of cellular proteostasis network”

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Chalk Talk

Mar 20, 2019 – Eric Strieter and Dan Hebert Labs

Ben Adams (Hebert Lab) “The Interplay of quality control pathways of the endoplasmic reticulum.”

Jiale Du (Strieter Lab) “Interrogating the Selectivity of Proteasome Associated Deubiquitinase UCH37.”

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Chalk Talk

Feb 13, 2019 – CBI Trainees!

Sandor Babik (Streiter Lab) “Interrogating Branched Ubiquitin Chains by NMR Spectroscopy and Computational Methods”

Samar Mahmoud (Chien Lab) “Exploring Lon-related pathways using a Non-Essential Phenotypic Suppressor Screen”

Javier Mas (Farkas Lab) “Understanding Macrophage Polarization and Re-Education in the Context of Cancer”

Weiyue Xin (Santore Lab) “The impact of curvature and solid mechanics on domain patterns in molecular thin materials”

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Chalk Talk

Jan 23, 2019 – Vince Rotello and Mike Knapp Labs

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Chalk Talk

Dec 12, 2018 – Jianhan Chen and Greg Tew Labs

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Chalk Talk

Nov 7, 2018 – Sloan Siegrist and Thai Thayumanavan Labs

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Chalk Talk

Oct 10, 2018 – Lynmarie Thompson and Richard Vachet Labs

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Chalk Talk

Sept 12, 2018 – Min Chen & Jeanne Hardy Labs