“Estimating Subclonal Populations from Structured DNA Sequencing Data“
Student Speaker – Shai He (Flaherty Lab)
“Antibody – Nanoparticle Conjugates for Targeted Delivery of Chemotherapeutics“
Student Speaker – Khushboo Singh (Thayumanavan Lab)
Past chalk talks
“Estimating Subclonal Populations from Structured DNA Sequencing Data“
Student Speaker – Shai He (Flaherty Lab)
“Antibody – Nanoparticle Conjugates for Targeted Delivery of Chemotherapeutics“
Student Speaker – Khushboo Singh (Thayumanavan Lab)
“A Cryptic Site on the Proteasome-Associated Deubiquitinase UCH37/UCHL5 is Required for Chain Editing and Degradation“
Student Speaker – Jiale Du (Strieter Lab)
“Real-time Monitoring of Transient Lipid-Lipid Interactions in Live Cell Membranes using a DNA Prob“
Student Speaker – Yousef Bagheri Zarringhabae (You Lab)
“Multiplex Imaging in Living Cells with Fluorogenic RNAs“
Student Speaker – Ru Zheng (You Lab)
“Studying allosteric sites on caspase-6 to aid the development of substrate-specific inhibitors“
Student Speaker: Irina Sagarbarria and Andrew J. Smith (Hardy Lab)
“Investigating alpha-synuclein aggregation using novel models of strain competition“
Student Speaker: Sarah Holec (Woerman Lab)
“Physical Origins of DnaK-substrate binding revealed through Physics-based modeling“
Erik Nordquist (J. Chen Lab)
Targeting Tau “The spread and aggregation of the protein tau has been linked to a variety of neurodegenerative diseases, known as tauopathies. Mounting evidence suggests that the spread of tau aggregates may underlie disease phenotype, however the mechanism for this toxicity is still unknown. The Rauch lab uses a variety of cell biology, biochemical, and in vivo techniques to characterize consequences of tau propagation in the central nervous system and to define/target the molecular requirements for tau spread. As the newest faculty to the BMB department, Jenny will give a brief overview of exciting projects that will be starting in her lab this upcoming January.”
Rauch Lab, new incoming BMB Assistant Professor beginning in January 2021.
Great talks and discussions with 78 attending this first-ever Zoom Chalk Talk!
Andrew Smith (Hardy lab) “Studying protein interactions to identify caspase exosites”
Nathan Canniff (Hebert lab) “Characterization of Putative ER Adaptors/Co-Chaperones TTC13 and TTC17”
Heather Bisbee (Strieter lab) “The Proteasomal Deubiquitinase UCH37 Promotes Degradation In Cellulo”
Katie Wahlbeck (Thompson lab) “Investigation of CheA Protein Dynamics with Solid State NMR”
Sarthak Saha (Perry Lab) “Protein Crystallography using X-ray compatible Microfluidic Devices”
Mengfei Huang (Schiffman Lab)“High-Performance Coatings Featuring Methylene Malonate Derivatives”
Sujeewa S. Lellupitiyage Don (Farkas Lab) “Tracking and Modulating Circadian Rhythms in Cell Culture Models of Breast Cancer”
Hanling Guo (Heuk Lab) “Searching for inhibitors of Type III secretion translocon assembly”
Teal Brechtel (Serio Lab) “Chaperone Titration as a Mechanism of Amyloid Appearance”
Aman Sharma (Jerry Lab) Estrogen-mediated R-loop formation associated with DNA damage may indicate individual vulnerability to breast cancer”
Can Özden (Stratton Lab) “CaMKII role in Long-Term Memory”
Elvan Cavaç and Kithmie MalagodaPathiranage (Martin Lab) “RNA for Next Generation Everything”
Carey Dougan (Peyton lab) “The Role of Cavitation in Traumatic Brain Injury (TBI)”
Christine Battle and Tommy Tashjian (Chien lab) “How to Get Away with Murder – Protein Destruction by Energy Dependent Proteases”
Minsoo Kim (Vierling Lab) “Breathing and Communication are Key to Life”
Weiyue Xin (Santore Lab) “Biological Membranes in the Materials World: How Curvature and Tension Influence the Assembly of Biomolecules”
Efecan Aral (Garman Lab) “Identifying effects of Fabry disease mutations to enable personalized medicine”
Rigumula Wu (You Lab) “Fluorogenic RNA-based Sensors for Quantitative Imaging in Living Cells”
Bin Zhao (You Lab) “Push It, Pull It: Critical Roles of Mechanical forces in biological processes”
Wenli Meng (Gierasch Lab) “Hsp 70 as hub of cellular proteostasis network”
Ben Adams (Hebert Lab) “The Interplay of quality control pathways of the endoplasmic reticulum.”
Jiale Du (Strieter Lab) “Interrogating the Selectivity of Proteasome Associated Deubiquitinase UCH37.”
Sandor Babik (Streiter Lab) “Interrogating Branched Ubiquitin Chains by NMR Spectroscopy and Computational Methods”
Samar Mahmoud (Chien Lab) “Exploring Lon-related pathways using a Non-Essential Phenotypic Suppressor Screen”
Javier Mas (Farkas Lab) “Understanding Macrophage Polarization and Re-Education in the Context of Cancer”
Weiyue Xin (Santore Lab) “The impact of curvature and solid mechanics on domain patterns in molecular thin materials”